Hereditary deficiency of ferroxidase (aka caeruloplasmin)

نویسنده

  • J I Logan
چکیده

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منابع مشابه

Effects of oxidative stress on some physiochemical properties of caeruloplasmin.

We report the effects of oxidative stress generated by low-intensity u.v. irradiation (366 and 254 nm), dialysis against ascorbate and isolated stimulated neutrophils on some physicochemical properties of caeruloplasmin. Low-intensity u.v. irradiation resulted in a loss of ferroxidase activity and 610 nm absorption, changes previously reported to occur during storage and manipulation of caerulo...

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Raised serum copper and caeruloplasmin levels in subjects taking oral contraceptives.

A marked increase in the serum copper and caeruloplasmin levels in 25 female subjects taking oral contraceptives is noted. The correlation between the copper and caeruloplasmin concentrations, together with the finding of normal urine copper levels in 10 of the subjects, suggests that the increased serum copper is due to increased caeruloplasmin synthesis.

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Undetectable caeruloplasmin values in a patient with autoimmune chronic active hepatitis.

Caeruloplasmin is an alpha 2 protein produced in the liver that is responsible for transporting copper in the blood. Caeruloplasmin values are usually high in patients with chronic liver diseases, including chronic active hepatitis: low values, however, are characteristic of Wilson's disease. The case of a 17 year old woman with very low caeruloplasmin values and chronic active hepatitis of the...

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Biochemical and pathological changes in tissues of Friesian cattle during the experimental induction of copper deficiency.

1. Copper deficiency was induced in five Friesian cattle offered a semi-synthetic diet containing less than 1 mgCu/kg. Changes in blood and liver Cu contents and in the Cu-containing enzymes, ferroxidase I (caeruloplasmin; EC 1.16.3.1) and monoamine oxidase (EC 1.4.3.4) of plasma and cytochrome oxidase (EC 1.9.3.1) of liver and skeletal muscle were monitored during Cu depletion. 2. Rapid decrea...

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Synovial fluid copper and related variables in rheumatoid and degenerative arthritis.

Copper, caeruloplasmin, transferrin, albumin, and total protein were measured in the serum and synovial fluid of 40 patients with rheumatoid arthritis and 40 patients with osteoarthrosis. A raised synovial fluid copper and caeruloplasmin have been found to be characteristic of rheumatoid effusions. The relation between copper and caeruloplasmin in synovial fluid differs from that in serum. Syno...

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عنوان ژورنال:
  • Journal of neurology, neurosurgery, and psychiatry

دوره 61 5  شماره 

صفحات  -

تاریخ انتشار 1996